Searchable abstracts of presentations at key conferences in endocrinology

ea0009p99 | Endocrine tumours and neoplasia | BES2005

Natural history of non-functioning pituitary adenomas managed conservatively at a single neuroendocrine unit

Hughes D , Sinclair D , Holland J , Heald A , Ciin L

An important issue for all endocrinologists involved in management of non-functioning pituitary adenomas (NFAs) not treated surgically at initial presentation is the frequency and duration of follow-up neuroimaging. Previous studies have described tumour enlargement in less than 15% of microadenomas (<1cm diameter) with macroadenomas (1cm diameter or more) showing a greater propensity for growth. With improvements in neuroimaging techniques we felt that it was timely to rev...

ea0005p49 | Clinical Case Reports | BES2003

Pituitary carcinoma presenting as an aggressive non-functioning adenoma

Gallagher L , Gattameneni R , Holland J , Davis J

A 44 year old man was referred with a 3-week history of progressive visual failure without headaches. He had bitemporal hemianopia but no evidence of endocrine dysfunction. MR scanning revealed a large pituitary macroadenoma with evidence of intralesional haemorrhage and compression of the optic chiasm. Endocrine testing revealed no evidence of a hormone excess syndrome or hypopituitarism. Transphenoidal hypophysectomy was performed urgently in May 2000 and his vision improved...

ea0007p80 | Endocrine tumours and neoplasia | BES2004

FSH-secreting pituitary gonadotroph adenoma producing ovarian hyperstimulation

Norris A , Hay C , Wilding M , McDowell G , Laing I , Holland J , McNeilly J , McNeilly A , Davis J

A 28-year-old Asian female presented with a 2 year history of abdominal pain and bloating and irregular heavy periods. She had a normal menarche and had 3 uncomplicated pregnancies after conceiving naturally, the last 4 years before presentation. Investigations showed LH 0.7 IU/l (normal range 2-14 IU/l), FSH 8.6 IU/l (2-14 IU/l), oestradiol 2030 pmol/l (80-300 pmol/l), prolactin 346 mU/l, and normal alpha GSU (0.3mcg/l). Ultrasound scanning revealed enlarged multicystic ovari...